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Selection guide for temperature control equipment in pharmaceutical factories.

Mar. 24. 2025

Selection guide for temperature control equipment in pharmaceutical factories.

Selection guide for temperature control equipment in pharmaceutical factories: Accurate temperature control empowers compliant production


In the pharmaceutical industry, temperature control directly affects drug quality, process safety, and compliance. Accurate temperature control equipment is crucial for ensuring drug stability and production continuity, from raw material synthesis, intermediate reaction to finished product sterilization. Shanghai Linbel Instrument focuses on providing high-precision temperature control solutions for pharmaceutical companies.


1、 Core elements for selecting pharmaceutical temperature control equipment


1. Temperature range and accuracy

The pharmaceutical process covers scenarios such as ultra-low temperature reactions (such as enzymatic hydrolysis at -180℃), high-temperature sterilization (300℃), and precision constant temperature cultivation (±0.1℃). The selection should specify the process temperature zone and prioritize equipment with wide coverage and precise temperature control. For example, the GDX series heating and cooling circulator supports wide temperature control from -80℃ to 300℃, meeting the needs of multiple scenarios.


2. Corrosion resistance and cleanliness requirements

The medium that the equipment comes into contact with (such as strong acids, organic solvents, etc.) should be made of corrosion-resistant materials such as 316L stainless steel and titanium alloy, and should comply with GMP's blind spot design. The DLSB series recirculating chiller adopts a fully enclosed circulation system to avoid the invasion of pollutants and is suitable for clean workshop environments.


3. Safety and compliance certification

Temperature control equipment must pass ISO9001 and CE certification, and have functions such as over temperature alarm, pressure protection, and leakage protection.


4. Energy efficiency and operation and maintenance costs

Choosing high-efficiency compressors (such as Secop, Emerson, Bitzer, etc.) and intelligent frequency conversion technology can reduce the overall energy consumption of older machines by 30%.



2、 Selection Guide


GDX series heating and cooling circulator: wide temperature range coverage

Applicable scenarios: raw material synthesis, freeze-drying process, stability testing

Product advantages:

Flexible temperature range: covering -80℃ ~ 300℃, customizable for higher / lower temperature models.

Precise temperature control: P.I.D. control, temperature fluctuation ≤ ±0.5℃, ensuring reaction consistency.

Multi machine linkage: supports parallel temperature control of multiple reaction vessels to improve pilot efficiency.

Selection suggestion:

The GDX series is recommended for processes that require rapid temperature rise and fall, with dual compressor refrigeration and a cooling rate of 3℃/min.


DLSB series recirculating chiller: efficient heat dissipation expert

Applicable scenarios: cooling of reactor jacket, cooling of semiconductor equipment

Model selection:

Open type DLSB-30: Minimum temperature -30℃, suitable for conventional cooling needs.

Sealed DLSB-120: Maximum temperature -120℃, suitable for ultra-low temperature processes (such as vaccine cryopreservation).

Core advantages:

Ultra quiet operation: Noise level ≤55dB, meeting GMP workshop noise standards.

Intelligent constant pressure: automatically adjusts flow rate to avoid pipeline blockage or bursting.


DFY series cold trap bath: a laboratory precision temperature control tool

Applicable scenarios: small-scale crystallization, biological enzyme reactions, material testing

Product performance:

Uniform temperature control: The temperature uniformity of the tank body is ±0.1℃, ensuring the reproducibility of the experiment.

Corrosion resistant tank body: made of stainless steel material, compatible with acidic or alkaline media.

Intelligent design: 7-inch touch screen, can preset programs, and one click start complex temperature control curves.


UC series heating circulator: combining safety and efficiency

Applicable scenarios: High temperature sterilization, catalyst activation, oil bath heating

Technical highlights:

Rapid heating: Heat up to 300℃ within 5 minutes to improve production efficiency.

Anti dry burning protection: Dual sensors monitor the liquid level in real-time and automatically cut off power for safety.

High temperature resistant pipeline: PTFE material pipeline can withstand a temperature of 350℃ to prevent aging and leakage of the body.